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Irving García Jiménez
Ph.D. 2021 |
On December 15, 2021, I obtained my Ph.D. in Cell Biology. I demonstrated that the RhoGEF known as ARHGEF17 contributes to the metastatic spread of lung cancer cells in immunocompetent mice. This RhoGEF is involved in the invasive and migratory responses elicited by Gi protein-coupled LPA receptors. ARHGEF17 is activated by Gbetagamma through the removal of inhibitory intramolecular interactions. My work was published in the Journal of Biological Chemistry. I continued my career as a Postdoctoral Fellow at the National Cancer Institute in Bethesda, MD, USA. |
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Víctor Manuel Color Aparicio
Ph.D. 2020 |
On October 15, 2020, I obtained my Ph.D in Pharmacology. I investigated the mechanisms by which endothelial cells adjust their morphology activated by the RhoJ GTPase directly stimulated by Intersectin-1, a multidomain GEF. Filopodia-like membrane projections on endothelial cells are fundamental and indicative of the process of tumor angiogenesis. This work was published in BBRC. |
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Alejandro Castillo Kauil
Ph.D. 2020 |
On October 29, 2020, I obtained my Ph.D. in Cell Biology. As part of my PhD work, I discovered that PDZ-RhoGEF is a Galpha-s signaling effector that allows this GEF to activate Cdc42 and promote the formation of filopodia-like membrane projections in endothelial cells. These findings extend our current understanding on the conventional mechanism by which this RhoGEF promotes actin stress fiber formation via Rho. This work was published in the Journal of Biological Chemistry. For this work I received the JBC's early career investigator Tabor Award and had the opportunity to continue my career as a postdoctoral fellow at the Barts Cancer Institute in London, UK. |
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Sendi Rafael Adame García
Ph.D. 2019 |
On June 28, 2019, I obtained my PhD in the Specialty of Cellular Biology. My work: “cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits” was published in the Journal of Biological Chemistry and was selected as representative of 'Signal transduction' for the 2019 retrospective collection called "The Year at JBC: 2019. I continued my career as a Postdoctoral Fellow at UCSD Moores Cancer Center in San Diego, California, USA. |
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Magda Hernández-Vásquez
Ph.D. 2017 |
On June 30, 2017 I obtained the Ph.D. in Pharmacology. My work: "Characterization of the signal transduction mechanisms of the Tumor Endothelial Marker 5 (TEM5/GPR124) in the angiogenic process" was published in the Journal of Biological Chemistry. During my training, I did a work visit at the lab of Jean-François Côté, at IRCM in Montreal.
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Ricardo Hernández-García
Ph.D. 2016 |
On June 30, 2016 I obtained the Ph.D. in Pharmacology. My work: "Endothelial RhoGEFs: systematic analysis of their expression profile in tumor and VEGF-stimulated endothelial cells" was published in Vascular Pharmacology. During my training, I contributed to the characterization of novel angiogenic signal transduction mechanisms that resulted in publications in the Journal of Biological Chemistry, Molecular Pharmacology and BBRC. In addition, I did a work visit at the University of California, Los Angeles in the laboratory of Dr. Luisa Iruela- Arispe. |
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Lydia Chávez-Vargas
Ph.D. 2016 |
On June 30, 2016 I obtained Ph.D. in Pharmacology. My work : "Molecular aspects of the interaction between the Protein Kinase A and the RacGEF P-Rex1 and its relevance in angiogenic signaling " was published in the Journal of Biological Chemistry. I received the "Tabor Award" by the ASBMB . As part of my training, I did a work visit at the NCVC in Osaka, Japan, in the laboratory of Dr. Naoki Mochizuki. |
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Evelyn Robles Molina
Ph D. 2014 |
I work in the area of regulatory issues and in the design and analysis of clinical studies for biotechnology products at Probiomed. |
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Ismael Bracho Valdés
Ph.D 2014 |
I am Assistant Professor of Pharmacology at the School of Medicine of the National Polytechnic Institute |
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Iliana Ramírez Rangel
Ph.D. 2011 |
I work for Starway SP ZOO SK, based in Warsaw, Poland, from where I travel around the world giving seminars and directing projects related to human development. |
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Jorge Carretero Ortega
Ph.D. 2009
M.S. 2005 |
I am a postdoc in the lab of Jesús Torres-Vázquez's at New York University. The focus of my work is elucidating how the endothelial receptor PlexinD1 (PlxnD1) transforms extracellular Semaphorin cues into signals that shape the anatomy of angiogenic blood vessels. To uncover the mechanisms that shape the reproducible vertebrate anatomy I am studying the development of the zebrafish 1ary Segmental (1ary Se) vessels. These evolutionarily conserved arterial angiogenic vessels arise from the aorta acquiring a simple and repetitive pattern, are made of few endothelial cells whose behaviors are easily imaged with cellular resolution and can be studied using genetic, chemical and embryological tools. |
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María Luisa Guzmán Hernández
Ph.D. 2008
M.S. 2004 |
After finishing my Ph.D. in Pharmacology I went to the National Institutes of Health in Bethesda, MD, USA as posdoc with Tamas Balla. I have been working on two interesting projects: one is concerned with the trafficking of the VEGF and another which explores the role of lipids transfer proteins in the distribution of phosphatidylinositol within various membranes. |
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Ivette Hernández Negrete
Ph.D. 2007 |
After getting my PhD I have been working in different labs in the UK. At the moment, I am part of the dementia group at Birmingham University where I study drug repurposing for Alzheimer’s and Parkinson’s disease. My main interest outside Academia involves science communication and public engagement. I do this mainly by writing for my blog and participating in outreach activities at schools and science fairs. |