José Vázquez Prado Ph.D.

 

Professor
Cinvestav 3D.
Department of Pharmacology
CINVESTAV-IPN
SNI II

Tel: 5747-3380
E-mail: jvazquez@cinvestav.mx


JVP Publications in PubMed

JVP Google academic

JVP en ResearchGATE

 

Research

G protein coupled receptors activate signaling pathways related to endothelial cell migration and angiogenesis. We study the molecular mechanisms of cell migration and angiogenesis with emphasis on the signal transduction pathways underlying the action of G protein coupled receptors and Rho family GTPases in endothelial cells.

Our studies are based on the hypothesis that RhoGEFs and their interacting proteins are potential drug targets of antiangiogenic molecules due to their role as critical transducers of angiogenic signals. Their inhibition offers an interesting potential to develop pharmacological strategies to prevent the progression of cancer and other pathologies.