Líneas de Investigación:
- Fisiopatología y farmacología de las enfermedades hepáticas: necrosis, fibrosis, cirrosis esteatohepatitis no alcohólica (NASH)
- Papel de las citocinas en las enfermedades hepáticas.
- Estrés oxidativo y su relación con las enfermedades del hígado.
Edición de Libros:
Título: Liver Pathophysiology: Therapies and Antioxidants
Editor: Pablo Muriel
Editorial: Elsevier
Año: 2017
ISBN: 9780128042748 |
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- Ocupa el lugar 104 de 2712 investigadores mexicanos en el “Ranking of scientists in Mexico Institutions according to their Google Scholar Citations public profiles”
- Ha publicado 19 capítulos en libros de casas editoriales reconocidas.
- Sus trabajos han sido citados en más de 4,000 ocasiones, índice H=36 (fuente: Google Scholar Citations public profiles).
- Ha graduado a más de 30 alumnos de posgrado.
Publicaciones Sobresalientes
- Muriel P., Mourelle M. Characterization of membrane fraction lipid composition and function of cirrhotic rat liver. Role of S-adenosyl-L-methionine. J. Hepatol. 14: 16-21, 1992. Factor de impacto ≥ 11.
- Muriel P., Suárez O.R., González P., Zuñiga L. Protective effect of S-adenosyl-L-methionine on liver damage induced by biliary obstruction in rats. A Histological, Ultrastructural and Biochemical Approach. J. Hepatol. 21: 95-102, 1994. Factor de impacto ≥ 11.
- Muriel P. Alpha-interferon prevents liver collagen deposition and damage induced by prolonged bile duct obstruction in the rat. J. Hepatol. 24: 614-621, 1996. Factor de impacto ≥ 11.
- Muriel P. Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. Biochem. Pharmacol. 56: 773-779, 1998. Factor de impacto ≥ 5.
- Fernández-Martínez E., Morales-Ríos M., Pérez-Álvarez V., Muriel P. Immunomodulatory effects of thalidomide analogs on LPS-induced plasmatic and hepatic cytokines in the rat. Biochem. Pharmacol. 68: 1321-29, 2004. Factor de impacto ≥ 5.
- Reyes-Gordillo K, Segovia J, Shibayama M, Vergara P, Moreno MG, Muriel P. Curcumin protects against acute liver damage in the rat by inhibiting NF-κB, proinflammatory cytokines production and oxidative stress. Biochim. Biophys. Acta, 1770: 989-996, 2007. Factor de impacto ≥ 4.
- Chávez E, Segovia J, Shibayama M, Tsutsumi V, Vergara P, Castro-Sánchez L, Salazar EP, Moreno MG, Muriel P. Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat. Liver Int. 30: 969-978, 2010. Factor de impacto ≥ 4.
- Aldaba-Muruato LR, Moreno MG, Shibayama M, Tsutsumi V, Muriel P. Protective effects of allopurinol against acute liver damage and cirrhosis induced by carbon tetrachloride: modulation of NF-κB, cytokine production and oxidative stress. Biochim. Biophys. Acta. 1820: 65-75, 2012. Factor de impacto ≥ 4.
- Muriel P, Gordillo KR. Role of oxidative stress in liver health and disease. Oxid. Med. Cell Longev, 2016, 2016. EDITORIAL. Factor de impacto ≥ 4.
- Reyes-Gordillo K, Shah R, Muriel P. Oxidative stress and inflammation in hepatic diseases: current and future therapy. Oxid. Med. Cell Longev. 2017, 2017. EDITORIAL. Factor de impacto ≥ 4.
Artículo más citado
- Muriel P, Garciapiña T, Pérez-Alvarez, Mourelle M. Silymarin protects against paracetamol-induced lipid peroxidation and liver damage. J. Appl. Toxicol. 12: 439-442, 1992. Más de 300 citas.